Best Fit Profiles
- age-related macular degeneration prevention and progression reduction
Macular protection and eye health
Lutein
Lutein is the primary carotenoid in the macular pigment. AREDS2 data supports lutein + zeaxanthin supplementation for reducing AMD progression. Effects are strongest in those with low dietary intake.
Evidence Level A
Evidence and Risk Labels
Evidence A/B/C reflects research maturity, and risk levels reflect monitoring needs. These labels support comparison, not diagnosis or treatment decisions.
See full scoring guideClinical Snapshot
- Effect Size
- Meaningful reduction in AMD progression in high-risk individuals; moderate macular pigment density improvement
- Safety
- Low Risk
Minimal; carotenodermia (skin yellowing) is harmless but indicates high intake. Smokers should avoid high beta-carotene alongside lutein.
Research Dosing
This reflects common ranges and protocols used in published studies, not personal medical advice.
- Typical Daily Dose
- 10 mg
- Timing
- With a fat-containing meal for absorption
- Protocol Duration in Studies
- Long-term (years) for AMD endpoints
AREDS2 used 10 mg lutein + 2 mg zeaxanthin; this combination is the standard reference.