2026-02-24
Alcohol, Aging, and Long-Term Health: What the Evidence Shows
Alcohol consumption interacts with aging biology in complex ways. This article covers the liver, brain, cardiovascular, and cancer evidence, plus what nutritional strategies can mitigate harm.
2026-02-20
Liver Enzyme Elevation Risk: Silymarin, NAC, and Berberine With Lifestyle First
Elevated liver enzymes improve most with weight, glucose, and alcohol correction. Silymarin, NAC, and berberine can be adjuncts in selected metabolic-risk contexts.
2026-02-16
Phosphatidylcholine: Liver Health, Cognitive Aging, and Choline Adequacy
Phosphatidylcholine is the dominant structural phospholipid in cell membranes and a major dietary choline source. It supports liver fat export, membrane integrity, and acetylcholine synthesis. Most adults are choline-insufficient; supplementation has meaningful implications for liver and brain aging.
2026-02-15
Silymarin (Milk Thistle): Liver Protection, MASLD Evidence, and Bioavailability Challenges
Silymarin (the active complex of milk thistle) has antioxidant and anti-inflammatory effects on hepatocytes. Evidence supports modest liver enzyme reduction in MASLD, though poor water solubility limits standard extract absorption. Phytosome forms show better bioavailability.
2026-02-12
TMG (Trimethylglycine): Methylation Support, Homocysteine Reduction, and Exercise Evidence
TMG (trimethylglycine/betaine) donates methyl groups to lower homocysteine and supports the methylation cycle alongside B12 and folate. It also shows consistent exercise performance benefits in multiple RCTs — a dual-purpose compound with a clean safety profile.