Jan 23, 2026Sulforaphane and NRF2: Broccoli Sprout Extract, Detoxification, and Cancer Prevention EvidenceSulforaphane is the most potent food-derived NRF2 activator. Broccoli sprout extract concentrates glucoraphanin (sulforaphane precursor) while myrosinase is needed for conversion. Clinical evidence for cancer chemoprevention and detoxification support is emerging.