Feb 12, 2026Inflammation Resolution: Specialized Pro-Resolving Mediators, Omega-3 Metabolites, and Beyond SuppressionMost anti-inflammatory strategies suppress inflammation. Resolution is an active, distinct process mediated by specialized pro-resolving mediators (SPMs) — resolvins, protectins, and maresins — derived from omega-3 fatty acids. Supporting resolution rather than just suppression may be the more effective long-term approach.