Feb 9, 2026Apigenin: CD38 Inhibition, NAD+ Preservation, and Sleep EvidenceApigenin inhibits CD38, an enzyme that consumes NAD+ — positioning it as an indirect NAD booster. It also has mild sleep-promoting and senolytic properties. Human evidence is limited but mechanistic rationale is solid.
Feb 6, 2026Cellular Senescence: What Zombie Cells Are, Senolytics, and the Evidence TimelineSenescent cells — sometimes called zombie cells — accumulate with age, secreting inflammatory signals (SASP) that damage neighboring tissue. Senolytics selectively eliminate them. This explainer covers the biology, the Mayo Clinic trials, and the current state of senolytic supplements and drugs.