Feb 19, 2026Resveratrol and Memory Retention: Evidence from a 26-Week Randomized Trial in Older AdultsWitte et al. (2014) found statistically significant memory improvements in adults 50–75 taking 200 mg/day resveratrol for 26 weeks, alongside improved hippocampal connectivity and glucose metabolism. Sample size was small (n=46) and findings require replication.
Feb 19, 2026Polyphenol Protocols in Cognition Clinics: Clinical Context and Evidence LimitsResveratrol, quercetin, and fisetin are used in some cognition-focused protocols, but human evidence is mixed and best interpreted as adjunctive support rather than primary therapy.
Feb 17, 2026NAD+ Precursor Supplementation and Cognitive Fatigue: Mechanism and Human EvidenceNAD+ precursors reliably elevate blood NAD+ in humans and activate mitochondrial energy pathways. Whether this translates to clinically meaningful reductions in cognitive fatigue requires larger, longer trials.
Feb 3, 2026Magnesium L-Threonate and Brain Health: Evidence from Human TrialsMagnesium L-threonate was developed to improve brain magnesium delivery. Human trials show modest cognitive improvements in older adults, though sample sizes are small and independent replication is limited.