2026-02-24
Menopause and Perimenopause: Supplement Evidence for Hot Flashes, Bone Loss, and Cognitive Symptoms
The menopausal transition accelerates bone loss, cognitive change, sleep disruption, and cardiovascular risk. Supplement evidence varies sharply: isoflavones have modest hot flash data; calcium and vitamin D are well-supported for bone; magnesium helps sleep. Black cohosh is used widely but evidence is mixed.
2026-02-21
Longevity Protocol for Women Over 50: Evidence-Based Priorities
Perimenopause and post-menopause mark a major metabolic and hormonal inflection point. This protocol covers the highest-leverage interventions for women over 50, grounded in current evidence.
2026-02-20
Osteopenia and Fragility: Protein, Vitamin D3, and K2 in a Training-First Plan
For osteopenia and fragility risk, mechanical loading and fall prevention remain primary. Vitamin D3, K2, whey protein, and creatine may provide selective additive support.
2026-02-18
Vitamin D3 and Telomere Attrition: Findings from the VITAL Randomized Trial
A VITAL sub-study (n=1,054, 4 years, 2,000 IU/day vitamin D3) found reduced leukocyte telomere attrition in the vitamin D group versus placebo. Omega-3 showed no significant effect. Telomere length is a surrogate marker; clinical outcome implications are uncertain.
2026-02-13
Vitamin D Deficiency and Immune Function: Prevalence, Evidence, and Supplementation Protocol
Vitamin D deficiency is common and associated with higher infection risk. Meta-analytic RCT evidence suggests supplementation can reduce acute respiratory infection risk, especially in deficient groups.