Stress reactivity and cognitive support

Phosphatidylserine

Small human trials suggest potential cognition and stress-response benefits, but evidence remains mixed across protocols.

Evidence Level B

Evidence and Risk Labels

Evidence A/B/C reflects research maturity, and risk levels reflect monitoring needs. These labels support comparison, not diagnosis or treatment decisions.

See full scoring guide

Clinical Snapshot

Effect Size
Modest cognition and stress-response support signal
Safety
Low Risk

May have additive calming effects when combined with multiple sedative-adjacent compounds.

Research Dosing

This reflects common ranges and protocols used in published studies, not personal medical advice.

Typical Daily Dose
100-300 mg
Timing
Morning or split morning/evening
Protocol Duration in Studies
4-12 weeks in stress/cognition interventions

Protocol timing can be personalized to daytime stress pattern.

Best Fit Profiles

  • high-cognitive-load schedules with stress reactivity

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