Energy metabolism, muscle, and sleep

Magnesium

Magnesium is involved in 300+ enzymatic reactions. Deficiency is common (estimated 40-60% of adults suboptimal). Supplementation improves sleep quality, reduces blood pressure, and supports glucose metabolism. Form significantly affects bioavailability.

Evidence Level A

Evidence and Risk Labels

Evidence A/B/C reflects research maturity, and risk levels reflect monitoring needs. These labels support comparison, not diagnosis or treatment decisions.

See full scoring guide

Clinical Snapshot

Effect Size
Meaningful improvement in sleep and metabolic markers in low-intake individuals; modest blood pressure reduction
Safety
Low Risk

Excess magnesium causes diarrhea; oxide form has poor bioavailability. Start at lower doses and titrate. Caution in severe kidney disease.

Research Dosing

This reflects common ranges and protocols used in published studies, not personal medical advice.

Typical Daily Dose
200-400 mg elemental magnesium
Timing
Evening dose supports sleep; with meals for metabolic effects
Protocol Duration in Studies
Ongoing; reassess if GI intolerance

Glycinate, malate, and threonate forms have better bioavailability and GI tolerance than oxide.

Best Fit Profiles

  • sleep quality improvement, blood pressure support, and metabolic health

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