Muscle preservation under stress and aging

HMB (Beta-Hydroxy Beta-Methylbutyrate)

Evidence supports preservation of lean mass and selected functional outcomes, especially when paired with resistance training.

Evidence Level B

Evidence and Risk Labels

Evidence A/B/C reflects research maturity, and risk levels reflect monitoring needs. These labels support comparison, not diagnosis or treatment decisions.

See full scoring guide

Clinical Snapshot

Effect Size
Modest lean-mass and functional-support benefit
Safety
Low Risk

Works best when paired with adequate protein intake and resistance exercise.

Research Dosing

This reflects common ranges and protocols used in published studies, not personal medical advice.

Typical Daily Dose
3 g
Timing
Split into 2-3 doses with meals
Protocol Duration in Studies
8-24 weeks in muscle-focused studies

Effect size is generally larger in less-trained and older populations.

Best Fit Profiles

  • deconditioning and recovery phases

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