2026-02-22
GERD and Acid Reflux in Aging: Mechanisms, Risks, and Evidence-Based Management
GERD prevalence increases with age and is often overtreated with PPIs, which carry their own risks. This article reviews the mechanisms, evidence-based lifestyle interventions, and where supplements fit.
2026-02-20
Osteoarthritis Symptom Load: Boswellia, Curcumin, and Ginger Trial Evidence
Adjunctive supplement evidence in osteoarthritis is strongest for modest pain and function support, with outcomes depending on extract quality, dose, and adherence.
2026-02-20
Irritable Bowel Symptom Load: Fiber-Probiotic Personalization and What to Track
IBS control is strongest with targeted diet structure and symptom tracking. Psyllium, selected probiotics, inulin titration, and ginger can be useful but require personalization.
2026-02-18
POLYCAD Trial: Spermidine Supplementation in Coronary Artery Disease — Design and Interim Context
The POLYCAD trial is testing 24 mg/day spermidine in 187 older adults with coronary artery disease for 48 weeks. Trial completion is expected August 2026 — no efficacy results exist yet. Prior cohort data from Eisenberg et al. 2016 provides the rationale.
2026-02-10
Resveratrol Protocols in Longevity Clinics: Evidence, Dosing, and Safety Context
How longevity clinics structure resveratrol protocols and what current human evidence does and does not support.