2026-02-24
Kidney Health and Aging: GFR Decline, Protein Intake, and Renoprotective Strategies
GFR declines ~1 mL/min/year after age 40. In early-stage CKD, protein restriction, blood pressure control, and avoiding nephrotoxic supplements (high-dose oxalate, aristolochic acid) are the primary levers. Potassium citrate and omega-3 have supportive evidence.
2026-02-23
Blood Sugar and Insulin Resistance: Supplement Protocol, Monitoring, and Evidence Summary
Insulin resistance precedes type 2 diabetes by years and independently drives cardiovascular risk, cognitive decline, and accelerated aging. Berberine, magnesium, alpha-lipoic acid, and chromium have the best evidence among supplements. This protocol integrates the strongest interventions with clear monitoring markers.
2026-02-19
Berberine for Metabolic Health: Evidence from Human Trials
Berberine activates AMPK through mild mitochondrial Complex I inhibition, producing improvements in glucose metabolism and modest weight loss in meta-analyses of clinical trials.
2026-02-19
Metabolic Syndrome: A Comprehensive Evidence-Based Protocol
Metabolic syndrome affects 1 in 3 adults and accelerates aging across every system. This protocol covers the interconnected drivers and the best-evidenced interventions for each component.
2026-02-10
Resveratrol Protocols in Longevity Clinics: Evidence, Dosing, and Safety Context
How longevity clinics structure resveratrol protocols and what current human evidence does and does not support.