2026-02-24
Joint Health and Cartilage Support: What the Evidence Shows
Cartilage has limited self-repair capacity, but several interventions modestly slow degradation and reduce symptoms. Here is what the clinical evidence supports for joint health in aging.
2026-02-20
Osteoarthritis Symptom Load: Boswellia, Curcumin, and Ginger Trial Evidence
Adjunctive supplement evidence in osteoarthritis is strongest for modest pain and function support, with outcomes depending on extract quality, dose, and adherence.
2026-02-19
Polyphenol Protocols in Cognition Clinics: Clinical Context and Evidence Limits
Resveratrol, quercetin, and fisetin are used in some cognition-focused protocols, but human evidence is mixed and best interpreted as adjunctive support rather than primary therapy.
2026-02-19
Glucosamine for Joints: Cartilage Evidence, Cardiovascular Signal, and Sulfate vs Hydrochloride
Glucosamine sulfate has modest RCT evidence for slowing cartilage loss and reducing joint pain in knee osteoarthritis. An unexpected but consistent epidemiological signal links glucosamine use with lower cardiovascular mortality — the mechanism may involve AMPK activation.
2026-02-12
Inflammation Resolution: Specialized Pro-Resolving Mediators, Omega-3 Metabolites, and Beyond Suppression
Most anti-inflammatory strategies suppress inflammation. Resolution is an active, distinct process mediated by specialized pro-resolving mediators (SPMs) — resolvins, protectins, and maresins — derived from omega-3 fatty acids. Supporting resolution rather than just suppression may be the more effective long-term approach.